Fig. 2: A cell-permeable miR-24-3p inhibitor is effective in the colon 5 days after one dose. | Cell Death & Disease

Fig. 2: A cell-permeable miR-24-3p inhibitor is effective in the colon 5 days after one dose.

From: Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation

Fig. 2

A Mice received an intraperitoneal (IP) or intravenous (IV) injection of 12.5 mg/kg control inhibitor or miR-24-3p (miR-24) inhibitor and colonic RNA was extracted 4 days later. n = 3 mice per group, for IP/IV representative of two independent experiments. Mean ± SD. B IP injections of 12.5, 6.25, and 2.5 mg/kg of a miR-24-3p inhibitor (miR-24) were tested for their efficacy at 4 days post injection. n = 3 mice per group, representative of two independent experiments. Mean ± SD. C Mice were IP injected with 2.5 mg/kg of a miR-24-3p inhibitor and were sacrificed 3, 5, or 7 days later. n = 3 mice per group. Mean ± SD. ***p < 0.001.

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