Fig. 1: Low expression of WTIP correlates with poor prognosis in AML patients.
From: WTIP upregulates FOXO3a and induces apoptosis through PUMA in acute myeloid leukemia
A Predicting the effect of WTIP expression on the survival of AML patients using PROGgeneV2. AML patients were classified into high and low WTIP expression subgroups (as per the median). Kaplan–Meier survival curves showed that patients with low WTIP expression had significantly shorter overall survival. P value was calculated by log-rank test. B Western blot analysis of WTIP expression in the indicated AML cell lines, GAPDH served as a loading control. C Western blot analysis of WTIP expression in mononuclear bone marrow cells derived from 60 AML patients and 17 healthy donors. P values were calculated by non-paired Student’s t-test (***P < 0.001).
