Fig. 1: Expression of miR-200b and NFIC in a mouse model of ATRA-induced NTDs. | Cell Death & Disease

Fig. 1: Expression of miR-200b and NFIC in a mouse model of ATRA-induced NTDs.

From: Nuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects

Fig. 1

A Relative expression of miR-200b in normal and ATRA-induced NTD embryos at E9.5 (n = 8). mRNA levels of NFIC (B) and NFIB (C) in E9.5 embryos from control and NTD groups (n = 8). D Protein abundance of NFIC in E9.5 mouse embryos (n = 9). E RNA expression correlation analysis for miR-200b and NFIC in NTD mouse embryos, as shown in the panel. The bar graph shows quantitative data from all experiments, which were independently performed in triplicate. *P < 0.05 vs. control group, “ns” represents no significance, compared to the control group.

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