Fig. 1: ScRNA-seq profiling of the cSCC tumor environments.

A Workflow of cSCC patients and healthy control sample processing for scRNA-seq. B Heatmap showing the expression of representative genes in each cluster. The top bars label the clusters corresponding to specific cell clusters. C Violin plots displaying the expression of well-known representative markers across the cell types identified in cSCC. D T-distributed stochastic neighbor embedding (t-SNE) plot shows the annotation for cell types. E Heatmap showing large-scale CNVs of normal KC and cSCC cells. The normalized CNV levels were shown, the red color indicates high CNV level and blue indicates low CNV level.