Fig. 2: BMP-7 inhibited the expression of Collagen-III and tubular epithelial to mesenchymal transition in kidneys of diabetic mice. | Cell Death & Disease

Fig. 2: BMP-7 inhibited the expression of Collagen-III and tubular epithelial to mesenchymal transition in kidneys of diabetic mice.

From: BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease

Fig. 2

a Representative micrographs show immunofluorescence staining of Collagen-III in different groups. DAPI staining(blue) represents cell nucleus, Bar = 100 um. Arrows (→) indicate positive expression. b Representative micrographs show immunohistochemical staining of α-SMA in different groups (magnification ×400). Arrows (→) indicate positive expression. Representative c Western blotting and d quantitative data were revealed the expression of E-cadherin, Collagen- III, Vimentin, in the kidney tissues in different groups, *P < 0.05 (n = 6).

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