Fig. 2: BMP-7 inhibited the expression of Collagen-III and tubular epithelial to mesenchymal transition in kidneys of diabetic mice.

a Representative micrographs show immunofluorescence staining of Collagen-III in different groups. DAPI staining(blue) represents cell nucleus, Bar = 100 um. Arrows (→) indicate positive expression. b Representative micrographs show immunohistochemical staining of α-SMA in different groups (magnification ×400). Arrows (→) indicate positive expression. Representative c Western blotting and d quantitative data were revealed the expression of E-cadherin, Collagen- III, Vimentin, in the kidney tissues in different groups, *P < 0.05 (n = 6).