Table 1 Correlation of Fascin expression and clinicopathological features in TNBC.

From: Fascin enhances the vulnerability of breast cancer to erastin-induced ferroptosis

 

N = 76

Fascin negative (N = 11)

Fascin positive (N = 65)

p value

Age (years, means ± SD)

 

61.0 ± 7.20

50.8 ± 9.44

0.001

Menses status

   

0.008

Premenopausal

35 (46.1%)

1 (9.1%)

34 (52.3%)

 

Postmenopausal

41 (53.9%)

10 (90.9%)

31 (47.7%)

 

Tumour size

   

1

≤2 cm

32 (42.1%)

5 (45.5%)

27 (41.5%)

 

>2 cm

44 (57.9%)

6 (54.5%)

38 (58.5%)

 

N status

   

0.782

N0

42 (55.3%)

7 (63.6%)

35 (53.8%)

 

N+

34 (44.7%)

4 (36.4%)

30 (46.2%)

 

Ki67

   

0.011

≤30

16 (21.1%)

6 (54.5%)

10 (15.4%)

 

>30

60 (78.9%)

5 (45.5%)

55 (84.6%)

 

Surgery

   

0.338

Lumpectomy

27 (35.5%)

2 (18.2%)

25 (38.5%)

 

Mastectomy

49 (64.5%)

9 (81.8%)

40 (61.5%)

 

Radiotherapy

   

1

No

33 (43.4%)

5 (45.5%)

28 (43.1%)

 

Yes

43 (56.6%)

6 (54.6%)

37 (56.9%)

 

Chemotherapy

   

0.583

No

7 (9.2%)

2 (18.2%)

5 (7.7%)

 

Yes

69 (90.8%)

9 (81.8%)

60 (92.3%)

 

Recurrence

   

0.472

Yes

4 (5.3%)

1 (9.1%)

3 (4.6%)

 

NO

72 (94.7%)

10 (90.9%)

62 (95.4%)

 

Vital status

   

0.472

Dead

4 (5.3%)

1 (9.1%)

3 (4.6%)

 

Alive

72 (94.7%)

10 (90.9%)

62 (95.4%)

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