Fig. 6: Inhibition of IL-6 combined with NVP-BEZ235 synergistically suppresses the PI3K/AKT/mTOR pathway in HCC cells.
From: The synergistic antitumor effect of IL-6 neutralization with NVP-BEZ235 in hepatocellular carcinoma

Combined treatment inhibited activation of the PI3K/AKT/mTOR pathway in HepG2 and Huh-7 cells. The expression pattern of PI3K/AKT/mTOR pathway-associated proteins was analyzed using western blotting.