Fig. 5: βc cytokines and βc receptor are overexpressed in IAV infected hβcTg mice. | Cell Death & Disease

Fig. 5: βc cytokines and βc receptor are overexpressed in IAV infected hβcTg mice.

From: Blocking the human common beta subunit of the GM-CSF, IL-5 and IL-3 receptors markedly reduces hyperinflammation in ARDS models

Fig. 5

hβcTg mice were infected with IAV (104 PFU, HKx31 strain) and culled at day 3 and day 6 post infection. Gene expression for βc cytokine (A) Gm-csf, (B) Il3, (C) Il5 and βc receptor (D) CSF2RB were analyzed in lung tissue by RTqPCR. n = 6; data are Mean ± SE; *p < 0.05, **p < 0.01, ***p < 0.001 one-way ANOVA.

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