Fig. 4: Cd44Δie mice exhibit higher innate immune cell infiltration upon DSS-induced colitis. | Cell Death & Disease

Fig. 4: Cd44Δie mice exhibit higher innate immune cell infiltration upon DSS-induced colitis.

From: Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop

Fig. 4

a IHC staining of F4/80 (macrophages) on colon sections. Arrowheads: mucosa, Arrows: submucosa. Scale bar: 50 µm. b IF staining of myeloperoxidase (MPO) (neutrophils) on colon sections. Scale bar: 50 µm. c qPCR of inflammation marker Tnfα expression in colon samples from Cd44Δie and Cd44+/+ mice. Reference genes: Gapdh and β-Actin. Error bars, ±SE. Inflammation: Mann–Whitney U-test. Regeneration: Student’s t test with unequal variances; *p < 0.05. N = number of mice.

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