Fig. 4: Upregulation of type I, III collagen and FN with MiR-7682-3p mimic. | Cell Death & Disease

Fig. 4: Upregulation of type I, III collagen and FN with MiR-7682-3p mimic.

From: The mmu_circRNA_37492/hsa_circ_0012138 function as potential ceRNA to attenuate obstructive renal fibrosis

Fig. 4

BUMPT cells were pre-transfected with either scramble mimic or miR-7682-3p mimic and co-treated with or without TGF-β1 for 24 h. A MiR-7682-3p expression by RT-qPCR analysis. B Type I, III collagen and FN expression by western blot analysis. C Quantification of protein band of type I collagen, type III collagen, and FN by grayscale analysis. Quantitative data are presented as the mean ± SD (n = 6 per group). *p < 0.05, TGF-β1 or miR-96-5p mimic group vs. control group; #p < 0.05, miR-7682-3p mimic with TGF-β1 group vs. TGF-β1 group.

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