Fig. 4: Expression of STMN1 in MVI is correlated with early recurrence.

A HCC patients with MVI were classified into High-STMN1 group and Low-STMN1 group according to STMN1 protein levels and estimated scores in MVI tissues. Classification of 79 MVI samples based upon the IHC scores was also exhibited (right). Scale bar: 100 um. B Comparison between traditional criteria and our novel STMN1 protocol of classifying early HCC patients with MVI. C, E Kaplan–Meier curves of recurrence and overall survival (OS) displayed the correlation between clinical outcome and risk classification stratified by STMN1 in MVI. D, F Kaplan–Meier curves of recurrence and OS showed the correlation between clinical outcome and risk classification of MVI predicted by H&E staining.