Fig. 3: PCLAF triggers pathways related to cell cycle regulation in RNA-seq data.
From: PCLAF promotes neuroblastoma G1/S cell cycle progression via the E2F1/PTTG1 axis
(A, B) Heatmap of Gene Ontology (GO) enriched terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) enriched terms colored by p-values; (C) The volcanic map was drawn according to the gene distribution. The abscissa is log2FoldChange, and the ordinate is -log10(p value); (D) Cluster heat map of 6 samples. Red represents high expressed genes and green represents low expressed genes; (E) The GO enrichment analysis results of differentially expressed genes; (F) The KEGG enrichment analysis results of differentially expressed genes. Select the top 20 pathways with the smallest p value for display; (G, H) Flow cytometry was used to analyze the cell cycle of neuroblastoma cell lines. (*p < 0.05, **p < 0.01, ***p < 0.001and ****p < 0.0001, and bar graphs represent the mean ± SEM).
