Fig. 2: Reduced adiposity in LXN-deficient mice. | Cell Death & Disease

Fig. 2: Reduced adiposity in LXN-deficient mice.

From: Latexin deficiency attenuates adipocyte differentiation and protects mice against obesity and metabolic disorders induced by high-fat diet

Fig. 2

A Representative pictures for WT and LXN−/− mice after feeding with HFD or ND for 23 weeks. B Comparison of body weight changes between WT and LXN−/− mice during the course of ND or HFD induction (n = 8). ND-WT, WT mice fed with ND; ND-KO, LXN−/− mice fed with ND; HF-WT, WT mice fed with HFD; HF-KO, LXN-/- mice fed with HFD. C, D Representative pictures for perirenal adipose tissue (C) and subcutaneous adipose tissue (D) collected from WT and LXN-/- mice after 23 weeks of HFD or ND feeding, and analysis of the weight. E, F Representative pictures for H&E-stained perirenal adipose sections (E) and subcutaneous adipose sections (F) collected from WT and LXN-/- mice after 23 weeks of HFD or ND feeding. Scale bar = 200 μm. Mean adipocyte size was calculated. All results were presented as mean ± SD, and P values were calculated with use of Student t test. *P < 0.05, and **P < 0.01.

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