Fig. 7: HA-JM2 injectable hydrogel inhibited postsurgical tumor recurrence. | Cell Death & Disease

Fig. 7: HA-JM2 injectable hydrogel inhibited postsurgical tumor recurrence.

From: Juxtamembrane 2 mimic peptide competitively inhibits mitochondrial trafficking and activates ROS-mediated apoptosis pathway to exert anti-tumor effects

Fig. 7

a Representative pictures of HA-JM2 injectable hydrogel. b Cell proliferation evaluation of B16F10 and 4T1 cells cultured with different hydrogels. c Schematic illustration of the in vivo tumor recurrence inhibition experimental protocol. d Representative gross observation images of post-surgical observation of mice in different groups at day 0 and 12. e Representative images and statistical analysis of recurrent tumors in different groups at day 12. f H&E staining of recurrent tumors obtained from different groups at day 12. g Ki67 immunofluorescence staining (green) and DAPI staining (blue) of recurrent tumors obtained from different groups at day 12. Statistical image displayed the number of Ki67-positive cells. *p < 0.05 and **p < 0.01 when the data was compared with the Control group.

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