Fig. 1: Single-cell RNA-seq analysis of the cytotoxic cells in the tumor tissue of HCC patients. | Cell Death & Disease

Fig. 1: Single-cell RNA-seq analysis of the cytotoxic cells in the tumor tissue of HCC patients.

From: Heterogeneity induced GZMA-F2R communication inefficient impairs antitumor immunotherapy of PD-1 mAb through JAK2/STAT1 signal suppression in hepatocellular carcinoma

Fig. 1

A The t-SNE map depicting the cytotoxic cells (red) in the (a), tumor tissues (b), adjacent tissues, and (c) tissues from eight HCC patients. B Bar plot depicting the ratio of cytotoxic cells in the tumor tissues and adjacent tissues for each HCC patient. C–D Expression t-SNE maps for the T cell exhaustion markers LAYN and CTLA4 in the tumor tissues and adjacent tissues.

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