Fig. 4: Leptin is upstream of DHH signaling in TME. | Cell Death & Disease

Fig. 4: Leptin is upstream of DHH signaling in TME.

From: Leptin secreted from testicular microenvironment modulates hedgehog signaling to augment the endogenous function of Leydig cells

Fig. 4

Leptin is upstream of DHH signaling in TME. A Schematics of experiment in which LSCs were treated with DHH agonist or antagonist in the presence of the TME, followed by extraction of condition media to perform cytokine antibody array. B Analysis results of the cytokine array between three different conditions (control, DHH agonist treatment, and DHH antagonist treatment). C Blots showing cytokine array with three experimental conditions. D Quantification of Leptin expression levels between the three conditions.

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