Fig. 8: H.pylori infection promotes STYX expression via c-Jun.

A Western blot analysis of STYX protein expression in AGS and HGC-27 cells infected with H.pylori (SS1 or 26695) at different time points. B qRT-qPCR analysis of STYX mRNA expression in GC cells infected with H. pylori at different time points. C Western blot was used to detect STYX transfected with c-Jun expression vector. D Western blot was used to detect STYX transfected with c-Jun siRNA. E Western blot was used to detect STYX in GC cells co-transfected with c-Jun siRNA and H.pylori (26695). F Working model for STYX promoting carcinogenesis and metastasis of GC.