Fig. 1: Gene expression profiling of primary uveal melanomas (UMs) based on metastatic status.
From: SLC25A38 as a novel biomarker for metastasis and clinical outcome in uveal melanoma
A Volcano plots showing differentially expression genes between metastatic tumors and non-metastatic tumors in TCGA UM cohort. B Heatmap showing the 89 most highly downregulated genes located on chromosome 3. Blue: decreased gene expression, red: increased gene expression. C Molecular landscape in 80 primary UMs of TCGA cohort. Mutation or expression status for six genes, the metastatic status of tumor sample, and chromosome 3 copy number alterations are indicated. D SLC25A38 was highly expressed in tumors with disomy 3 in TCGA UM cohort.
