Fig. 2: Model accuracy and survival analyses in UM.
From: SLC25A38 as a novel biomarker for metastasis and clinical outcome in uveal melanoma
A–F Receiver Operator Curves based on different feature sets in TCGA cohort (A–C) and GSE22138 cohort (D–F). The predictive accuracy of SLC25A38 expression for risk of metastasis was superior to that of other biomarkers. The P-value in light blue in B indicates Binary SLC25A38 vs BAP1 Mut, and the P-value in dark blue in B indicates Binary SLC25A38 vs SF3B1 Mut. The P-value in light blue in C indicates Binary SLC25A38 vs Binary BAP1, and the P-value in dark blue in C indicates Binary SLC25A38 vs GEP Class. G–I Survival curves based on SLC25A38 expression level. Low expression of SLC25A38 predicted poor clinical outcomes not only in all patients but also in patients without metastasis or patients with disomy 3 in TCGA UM cohort. AUC Area Under Curve.
