Fig. 1: The presence of pyroptosis in the podocytes of MN patients. | Cell Death & Disease

Fig. 1: The presence of pyroptosis in the podocytes of MN patients.

From: Complement induces podocyte pyroptosis in membranous nephropathy by mediating mitochondrial dysfunction

Fig. 1

A The relative mRNA levels of pyroptosis-related genes in the glomeruli of healthy controls and MN patients. B Immunohistochemical detection of the protein level of pyroptosis-related proteins in renal cortical sections of healthy controls and MN patients (scale bar = 50 μm). The quantification of the average optical density is shown in the panel below (12–81 glomeruli of each group were analyzed). C The colocalization of pyroptosis-related proteins and synaptopodin in renal cortical sections of MN patients (scale bar = 50 μm). D The ratios of fluorescence intensity of pyroptosis-related proteins to synaptopodin of Panel (C) were calculated by the ImageJ program (scale bar = 50 μm). The data represent the mean ± SEM. *p < 0.05.

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