Fig. 6: The presence of pyroptosis in the kidney of PHN rats. | Cell Death & Disease

Fig. 6: The presence of pyroptosis in the kidney of PHN rats.

From: Complement induces podocyte pyroptosis in membranous nephropathy by mediating mitochondrial dysfunction

Fig. 6

A Silver staining of urine protein of normal control rats and PHN rats. B Electron microscopy observation of renal morphology in normal control and PHN rats. Triangles (Δ), electron-dense deposits. C Levels of pyroptosis-related mRNAs in glomeruli of normal control (NC) and PHN rats. D Western blotting of pyroptosis-related molecules in the renal cortex of normal control rats and PHN rats. E Immunohistochemical staining of pyroptosis-related molecules in renal sections of normal control rats and PHN rats (scale bar = 50 μm). Quantification of the average optical density is shown in the right panel (27–256 glomeruli of each group were analyzed). The data in (C) and (E) represent the mean ± SEM, *p < 0.05.

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