Fig. 6: BCL6 knockout promotes CD36 expression both in vivo and in vitro. | Cell Death & Disease

Fig. 6: BCL6 knockout promotes CD36 expression both in vivo and in vitro.

From: B-cell lymphoma 6 alleviates nonalcoholic fatty liver disease in mice through suppression of fatty acid transporter CD36

Fig. 6

Relative mRNA levels of genes related to (A) FFA oxidation, (B) synthesis, and (C) uptake in the livers of BCL6-flox and BCL6-CKO mice fed an HFD for 16 weeks. D Protein level of BCL6 and genes related to FFA uptake in the livers of mice. Relative mRNA levels of gene related to (E) FFA oxidation, (F) synthesis, and (G) uptake in the livers of BCL6-flox and BCL6-CKO mice fed an HFD for 16 weeks. D Protein level of BCL6 and genes related to FFA uptake in the livers of mice. Relative mRNA levels of gene related to (E) FFA oxidation, (F) synthesis, and (G) uptake in the LO2 cells stimulated with PA (0.3 mM) for 24 h after transfected with Ad-Scr sh (as a control) or Ad-BCL6 sh for 48 h. n = 3 in each group. H Protein level of BCL6 and genes related to FFA uptake in the LO2 cells. Data represent the mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001 and n.s. indicates no significance between the two indicated groups.

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