Fig. 1: E2F1 deregulation in human GC tissues is associated with poor prognosis.
From: The miR-532-E2F1 feedback loop contributes to gastric cancer progression
A E2F1 expression analysis in 211 normal tissues and 408 GC tissues from TCGA database. B E2F1 expression was correlated with the clinical grade of GC in TCGA dataset. C Representative images of HE staining and E2F1 IHC staining in GC tissues and matched normal adjacent tissue (NAT) (n = 100). D Total IHC score of E2F1 in GC tissues and matched NATs (n = 100). E Kaplan–Meier analysis of survival of patients with GC stratified by E2F1 expression. F, G Western blot analysis of E2F1 protein levels in another 21 paired GC tumor tissues (T) and normal adjacent tissues (N) samples. F: Representative images; G: quantitative analysis. *P < 0.05; *** P < 0.001.
