Fig. 7: CircLIFR inhibits HCC cell progression via GSK-3β.

A, B Colony formation assay showing the effect of GSK-3β and circLIFR on cell proliferation in Huh7 and SNU387 cells. C, D Transwell migration assay performed to examine the effect of GSK-3β and circLIFR on cell migration in Huh7 and SNU387 cells. E, F Transwell invasion assay performed to examine the effect of GSK-3β and circLIFR on cell invasion in Huh7 and SNU387 cells. Representative images taken at a magnification of ×100. Scale bar: 100 μm. Data represent means ± SD of three independent experiments. *P < 0.05.