Fig. 1: SH2B3 was diminished in lung cancer tissues and cells.

A qRT-PCR analysis of SH2B3 mRNA levels in human lung cancer tissues (n = 40). B IHC assay to examine SH2B3 protein levels in human lung cancer tissues. C Bioinformatic analysis of SH2B3 mRNA level in human lung cancer tissues from UALCAN database. D Bioinformatic analysis of SH2B3 mRNA level in lung cancer tissues from patients at different stages from UALCAN database. E qRT-PCR analysis of SH2B3 mRNA levels in cultured lung cancer cell lines. F Western blotting to examine SH2B3 protein levels in cultured lung cancer cell lines. ***P < 0.001 and **P < 0.01.