Fig. 3: SH2B3 suppressed EMT and cell migration and invasion of lung cancer. | Cell Death & Disease

Fig. 3: SH2B3 suppressed EMT and cell migration and invasion of lung cancer.

From: TGF-β1/SH2B3 axis regulates anoikis resistance and EMT of lung cancer cells by modulating JAK2/STAT3 and SHP2/Grb2 signaling pathways

Fig. 3

A Transwell assay to measure invasion capacity of transfected cancer cells. B Scratch wound-healing assay to determine the migration ability of transfected cancer cells. C Immunostaining to test E-cadherin and N-cadherin protein levels in transfected cancer cells. D Western blotting to measure levels of EMT-related markers including E-cadherin, N-cadherin, slug, vimentin, MMP-2, and MMP-9 in transfected cancer cells. ***P < 0.001 and **P < 0.01.

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