Fig. 5: miR-140-3p and miR-335 can partially rescue the tumor-suppression effects caused by the knockdown of circSCAF8 in PCa cells. | Cell Death & Disease

Fig. 5: miR-140-3p and miR-335 can partially rescue the tumor-suppression effects caused by the knockdown of circSCAF8 in PCa cells.

From: CircSCAF8 promotes growth and metastasis of prostate cancer through the circSCAF8-miR-140-3p/miR-335-LIF pathway

Fig. 5

A, B EDU and colony formation assays were carried out to detect the proliferation ability of PC3 cells in the circSCAF8 knockdown group after being transfected with miR-140-3p inhibitors, miR-335 inhibitors, and miR-140-3p/miR-335 inhibitors, respectively. C–E The invasion and migration abilities of PC3 cells with circSCAF8 knockdown treated with miR-140-3p inhibitors, miR-335 inhibitors, and miR-140-3p/miR-335 inhibitors were measured by transwell invasion assay C, transwell migration assay (D), and wound healing assay (E). Error bars represent the SD of three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001. PCa prostate cancer, EDU 5-ethynyl2′deoxyuridine.

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