Fig. 1: Mice treated with rotenone showed PD-like pathological changes and motor dysfunction. | Cell Death & Disease

Fig. 1: Mice treated with rotenone showed PD-like pathological changes and motor dysfunction.

From: circ-Pank1 promotes dopaminergic neuron neurodegeneration through modulating miR-7a-5p/α-syn pathway in Parkinson’s disease

Fig. 1

A, B Number of TH-positive cells in the brain tissue of PD model mice treated with rotenone; scale bars, 500 μm (n = 4). C, D Western blot analysis of the TH protein levels in the SN of PD model mice treated with rotenone (n = 4). E–N Pole-climbing test E, F, field test (G–J) and step measurement K–N were performed on PD model mice treated with rotenone to evaluate the exercise ability (n = 8). Data are presented as mean ± SD. *P < 0.05, **P < 0.01.

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