Fig. 4: Inhibition of IRAR reduces ischemia-reperfusion (IR)-induced production of chemokines and infiltration of immune cells. | Cell Death & Disease

Fig. 4: Inhibition of IRAR reduces ischemia-reperfusion (IR)-induced production of chemokines and infiltration of immune cells.

From: LncRNA IRAR regulates chemokines production in tubular epithelial cells thus promoting kidney ischemia-reperfusion injury

Fig. 4

A–C ELISA of CXCL1 (A), CXCL2 (B), CCL2 (C) in the kidney 24 h after renal IR (n = 6–8). D Immunofluorescence staining of Gr-1 and F4/80 in the kidney 6 h after renal IR. Gr-1 was used as a marker of neutrophils and F4/80 was used as a marker of macrophages. Scale bar, 100 μm (n = 6–8). E Quantification of Gr-1-positive neutrophils and F4/80-positive macrophages in the kidneys. Data represent mean ± SEM. n = 4. *p < 0.05, **p < 0.01.

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