Fig. 6: Inhibition of CXC chemokine receptor 2 (CXCR2) attenuates ischemia-reperfusion (IR)-induced inflammation. | Cell Death & Disease

Fig. 6: Inhibition of CXC chemokine receptor 2 (CXCR2) attenuates ischemia-reperfusion (IR)-induced inflammation.

From: LncRNA IRAR regulates chemokines production in tubular epithelial cells thus promoting kidney ischemia-reperfusion injury

Fig. 6

The mice received intraperitoneal administrations of antagonist of CXCR2 (CXCR2(-)-IR) or vehicle (NC-IR) 1 h prior and 1 h after renal IR. A Immunofluorescence staining of Gr-1 in the kidney 6 h after renal IR. Scale bar, 100 μm. B Quantification of Gr-1-positive neutrophils. C Concentration of serum creatinine 24 h after renal IR. D ELISA of IL-6 in the kidney 6 h after renal IR. Data represent mean ± SEM. n = 6–8. **p < 0.01.

Back to article page