Fig. 1: DLBCL datasets revealed that IDO1 was overexpressed in DLBCL and could be a predictive marker for DLBCL. | Cell Death & Disease

Fig. 1: DLBCL datasets revealed that IDO1 was overexpressed in DLBCL and could be a predictive marker for DLBCL.

From: IDO1 plays a tumor-promoting role via MDM2-mediated suppression of the p53 pathway in diffuse large B-cell lymphoma

Fig. 1

A–C IDO1 expression in DLBCL and normal tissues from GSE12195 (A), GSE56315 (B), and TCGA DLBCL (C). D, E Receiver operating characteristic (ROC) curves calculated the sensitivity and specificity of the IDO1 expression level for the prediction of DLBCL in the GSE12195 (D) (AUC = 0.995) and GSE56315 (E) (AUC = 1.000) datasets. F, G PRC analysis calculated sensitivity and specificity of the IDO1 expression level for the prediction of DLBCL in the GSE12195 (F) (AUC = 0.999) and GSE56315 (G) (AUC = 1.000) datasets. Statistical analysis was analyzed with a two-sided student’s t-test. *P < 0.05 and ****P < 0.0001.

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