Fig. 6: Targeted silencing of eIF5A2 increases cisplatin sensitivity in vivo.
From: Eukaryotic initiation factor 5A2 mediates hypoxia-induced autophagy and cisplatin resistance
A The stripped NSCLC tissues were arranged as shown. B Tumor volume curve showing that the nude mice silenced for eIF5A2 and treated with cisplatin had the smallest tumor volume, which was statistically significant. C There was no statistical difference in the body weight of nude mice among the groups. D–F According to the results of IHC (D), the nude mice silenced for eIF5A2 and treated with cisplatin had the lowest expression of Ki67 (E) and the highest level of TUNEL staining (F). *P < 0.05, **P < 0.01.
