Fig. 2: GDF15 is identified as a major glycoprotein in IRPC. | Cell Death & Disease

Fig. 2: GDF15 is identified as a major glycoprotein in IRPC.

From: N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells

Fig. 2

A Pearson correlation coefficient heatmap of quadruplicates indicates reliability of experiment. B Numbers of glycoproteins, glycopeptides, intact N-glycopeptides (IGPs), and glycans identified are presented. C Volcano plots indicate differentially expressed glycoproteins. p < 0.05. D Heatmap shows differentially expressed glycotypes. E Heatmap displays proteins modified by up-regulated glycotypes. Red indicates up-regulation, blue indicates down-regulation, and gray indicates no difference. N is HexNAc, H is Hex. F is Fucose. Cartoon symbols used for glycans (see inset) conform to the standard representation recommended by the Consortium for Functional Glycomics.

Back to article page