Fig. 1: EBV-miR-BART22 expression is upregulated in nasopharyngeal carcinoma. | Cell Death & Disease

Fig. 1: EBV-miR-BART22 expression is upregulated in nasopharyngeal carcinoma.

From: Epstein–Barr virus-encoded microRNA BART22 serves as novel biomarkers and drives malignant transformation of nasopharyngeal carcinoma

Fig. 1

A The cluster heat maps showing the GSE54161 different expressed microRNAs in 2 lines of EBV positive and 2 lines of EBV-negative nasopharyngeal carcinoma cells. The blue and red stripes represent downregulated and upregulated microRNAs, respectively. B The cluster heat maps showing the GSE118720 different expressed microRNAs in 7 NPC biopsy specimens and 4 normal nasopharyngeal mucosal specimens. The blue and red stripes represent downregulated and upregulated microRNAs, respectively. C Microarray analysis was performed to identify EBV and nasopharyngeal carcinoma-associated microRNAs. Expression levels were analyzed in GSE54161, GSE118720. To narrow the range of values, the cut off with p-value < 0.01 and |fold change (FC)| > 2, as shown in the flowchart. These data were integrated with tighter standards to identify the potential esophageal carcinoma and EBV-associated microRNAs (two microRNAs).

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