Fig. 7: Overexpression of lncRNA HEPFAL inhibits tumor growth of cell xenografts in nude mice.
A 1 × 106 HCCLM3 cells were injected into nude mice and removed after 30 days. B Measure and count the weight of the tumor(n = 4). C The tumor volumes were measured every three days after the cells were injected for 14 days. D HCCLM3 cells were injected into nude mice and treated with erastin after 30 days. E Measure and count the weight of the tumor (n = 4). F The tumor volumes were measured every three days after the cells were injected for 14 days. G SLC7A11 expression was detected by IHC and IF. H Western blot analysis of NRF2, ACSL4, SLC7A11, FSP1, and GPX4 protein level in tumor tissues. I Western blot analysis of NRF2, ACSL4, SLC7A11, FSP1, and GPX4 protein levels in tumor tissues after erastin treatment. *P < 0.05.
