Fig. 5: Distribution of rhodopsin and vesicles in the photoreceptor cells of the retinas of Mdm1+/+ and Mdm1−/− mice. | Cell Death & Disease

Fig. 5: Distribution of rhodopsin and vesicles in the photoreceptor cells of the retinas of Mdm1+/+ and Mdm1−/− mice.

From: Mdm1 ablation results in retinal degeneration by specific intraflagellar transport defects of photoreceptor cells

Fig. 5

a Immunofluorescence staining of Mdm1 (red) and rhodopsin (green) in the photoreceptor cells of Mdm1+/+ and Mdm1−/− mice at the indicated ages. Representative images are shown (n > 5 per group). Scale bar, 10 μm. b TEM images of the photoreceptor cells of the retina in Mdm1+/+ and Mdm1−/− mice. Arrows indicate vesicles in the IS. Scale bar, 1 μm. RPE, retinal pigmented epithelial cells; OS, outer segment; CC, connecting cilium; BB, basal body; IS, inner segment; ONL, outer nuclear layer; INL, inner nuclear layer; m, mitochondria.

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