Table 1 The regulation of caspase-2 by ncRNAs in cancer.
Type | ncRNAs | Cancer | Capase-2 regulation | Effect on tumor | References |
|---|---|---|---|---|---|
miRNAs | miR-708 | Bladder carcinoma | Inhibition (↓) | Promotion | [60] |
miR-383 | Epithelial ovarian cancer | Inhibition (↓) | Promotion | [61] | |
Colon cancer | [62] | ||||
miR-210 | Colorectal cancer | Activation (↑) | Suppression | [63] | |
miR-1247-3p | Gastrointestinal cancer | Inhibition (↓) | Promotion | [64] | |
miR-34a | Liver cancer | Inhibition (↓) | Promotion | [65] | |
miR-183 | Non-small cell lung cancer | Inhibition (↓) | Promotion | [66] | |
miR-494 | [67] | ||||
miR-182-5p | [68] | ||||
miR-149 | Glioma | Inhibition (↓) | Promotion | [69] | |
Acute myeloid leukemia | [70] | ||||
lncRNAs/miRNAs | HOTAIR/miR-125a-5p | Colon cancer | Inhibition (↓) | Promotion | [88] |
TPT1-AS1/miR-3156-5p | Breast cancer | Activation (↑) | Suppression | [89] |