Table 2 Univariate and multivariate analysis of factors associated with overall survival in GC patients.
 | Overall survival |  |
---|---|---|
 | HR (95% CI) | P value |
Univariate analysis | Â | Â |
 Age (≤60 years vs. >60 years) | 1.32 (0.97–1.80) | 0.082 |
 Sex (male vs. female) | 0.72 (0.47–1.10) | 0.130 |
 Tumor diameter (≤5 cm vs. >5 cm) | 2.31 (1.71–3.12) | <0.001 |
 Surgical type (subtotal gastrectomy vs. total gastrectomy) | 2.07 (1.50–2.85) | <0.001 |
 Tumor differentiation (poor vs. well/moderate) | 0.44 (0.31–0.61) | <0.001 |
 pT stage (T1–3 vs. T4) | 3.39 (2.44–4.69) | <0.001 |
 pN stage (N0 vs. N+) | 7.15 (4.64–11.02) | <0.001 |
 pTNM stage (I–II vs. III) | 7.75 (5.31–11.30) | <0.001 |
 Lymphovascular invasion (present vs. absent) | 0.43 (0.31–0.60) | <0.001 |
 CRABP2 expression (negative vs. positive) | 1.57 (1.16–2.11) | 0.003 |
Multivariate analysis | Â | Â |
 Age (≤60 years vs. >60 years) | 1.24 (0.9–1.7) | 0.190 |
 Sex (male vs. female) | 0.66 (0.43–1.02) | 0.059 |
 Tumor diameter (≤5 cm vs. >5 cm) | 1.11 (0.79–1.55) | 0.545 |
 Surgical type (subtotal gastrectomy vs. total gastrectomy) | 1.23 (0.9–1.68) | 0.198 |
 Tumor differentiation (poor vs. well/moderate) | 0.9 (0.63–1.28) | 0.545 |
 pT stage (T1–3 vs. T4) | 1.02 (0.68–1.52) | 0.936 |
 pN stage (N0 vs. N+) | 1.98 (0.94–4.19) | 0.073 |
 pTNM stage (I–II vs. III) | 3.71 (1.77–7.8) | 0.001 |
 Lymphovascular invasion (present vs. absent) | 0.72 (0.51–1.01) | 0.054 |
 CRABP2 expression (negative vs. positive) | 1.41 (1.01–1.98) | 0.043 |