Fig. 2: Zymosan-A protected the intestinal issue against IR-induced injury.
From: Zymosan-A promotes the regeneration of intestinal stem cells by upregulating ASCL2
C57BL/6 mice were intraperitoneally injected with 25 mg/kg/time of Zymosan-A 24 h before and 2 h before 9.5 Gy TBI. A Representative images of HE-stained intestinal sections with the indicated treatment at 4, 24, 48, and 84 h. B Number of viable crypts. C Villus length. D Depth of viable crypts. E Representative images of Ki-67 immunohistochemical staining intestinal sections with the indicated treatment at 24 and 48 h. F The Ki-67+ cells per crypts. G Representative images of TUNEL immunohistochemical staining intestinal sections with the indicated treatment at 24, 48, and 84 h. H The TUNEL+ cells per crypts. The data were presented as mean ± SD. *P < 0.05, **P < 0.01, and ***P < 0.001 for control versus Zymosan-A treatment.
