Table 1 Clinical characteristics of the total population.

From: Mutated lncRNA increase the risk of type 2 diabetes by promoting β cell dysfunction and insulin resistance

 

TT

TC

CC

p value

N

90

1,554

14,469

–

NGT

23

481

6,634

<0.0001

Pre-diabetes

37

618

5,092

T2DM

30

455

2,743

Gender (male/female)

36/54

691/863

6017/8452

0.0858

Age (year)

54.9 ± 10.0

58.3 ± 7.9

54 ± 11.1

<0.0001

BMI (kg/m2)

25.4 ± 5.1

25.1 ± 3.5

24.6 ± 3.3

<0.0001

HbA1c (%)

6.0 (5.5, 6.4)

5.7 (5.4, 6.3)

5.7 (5.4, 6.1)

<0.0001

FPG (mmol/L)

5.8 (5.4, 6.8)

6.0 (5.5, 6.7)

5.7 (5.1, 6.3)

<0.0001

PG30 (mmol/L)

9.6 (8.8, 11.5)

10.3 (9.3, 11.8)

9.4 (8.3, 11.1)

<0.0001

PG2H (mmol/L)

8.3 (6.7, 12.6)

8.5 (6.8, 11.3)

7.5 (5.8, 9.5)

<0.0001

  1. Data are presented as mean ± standard deviation or median (interquartile range). N. Kruskal Wallis test for continuous variables and χ2 test for categorical variables were applied to assess the differences among three groups.
  2. NGT normal glucose tolerance, T2DM type 2 diabetes mellitus, BMI body mass index, HbA1c glycated hemoglobin A1c, FPG fasting plasma glucose, PG30 30 min plasma glucose, PG2H 2 h plasma glucose.
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