Fig. 1: RHBDL2 is upregulated in PC and positively related to worse prognosis of PC patients. | Cell Death & Disease

Fig. 1: RHBDL2 is upregulated in PC and positively related to worse prognosis of PC patients.

From: RHBDL2 promotes the proliferation, migration, and invasion of pancreatic cancer by stabilizing the N1ICD via the OTUD7B and activating the Notch signaling pathway

Fig. 1

A, B Expression of RHBDL2 in the HPDE cells and six PC cell lines (CFPAC-1, MIA PaCa-2, SW1990, AsPC-1, PANC-1, and BxPC-3) was determined by qRT-PCR and Western blot assays, respectively. C, D qRT-PCR and Western blot analysis of RHBDL2 expression in PC tissues and adjacent non-tumor tissues. IHC assay confirmed the levels of RHBDL2 expression in the PC tissues compared with that in the adjacent non-tumor tissues (E), and in metastatic PC tissues compared with that in non-metastatic PC tissues (F), respectively (n = 95). Scale bar: 100 μm. G Kaplan-Meier analysis of PC patients with high/low RHBDL2 expression. *P < 0.05, **P < 0.01, ***P < 0.001.

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