Fig. 3: LINC02551 accelerates HCC progression in vivo. | Cell Death & Disease

Fig. 3: LINC02551 accelerates HCC progression in vivo.

From: ALKBH5-mediated m6A modification of lincRNA LINC02551 enhances the stability of DDX24 to promote hepatocellular carcinoma growth and metastasis

Fig. 3

a Subcutaneous transplantation model generated with stable 97H-Vec and 97H-LINC02551 cell lines. When the mice were sacrificed, the tumors were removed. b The statistical analysis of the weight and volume of the subcutaneous tumors. c The results from the orthotopic transplantation model established with nude mice using 97H-luc-LINC02551 or vector cells. d Statistical analysis of the liver nodule numbers and luciferase activity. e, f H&E and other stains applied to proteins in liver-bearing tumors. g Results of tail vein injection of HLF-luc-LINC02551 or vector cells in nude mice. After sacrifice, the lungs were removed and photographed. The statistical analysis is presented in the right panel. Statistical analysis was performed using Student’s t-tests. Data are mean ± SEM. *P < 0.05, **P < 0.001, ***P < 0.0001.

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