Fig. 1: PRMT3 is overexpressed in GBM and negatively correlated with prognosis. | Cell Death & Disease

Fig. 1: PRMT3 is overexpressed in GBM and negatively correlated with prognosis.

From: PRMT3 drives glioblastoma progression by enhancing HIF1A and glycolytic metabolism

Fig. 1

A, B The differential expression of PRMT genes in the TCGA GBM (A) and LGG (B) datasets. C PRMT3 expression levels in grade IV GBMs are the highest among TCGA gliomas. D Kaplan-Meier survival curve for PRMT3 in GBMs. Figure was created using GlioVis data portal (http://gliovis.bioinfo.cnio.es/). E Immunostaining of PRMT3 in the normal cerebral cortex, HGG, and LGG tissues from the Human Protein Atlas. Scale bars, 100 μm. F Western blot of PRMT3 expression in human astrocytes and GSC11, GSC20, GSC28, GSC248, GSC262, GSC267, GSC295, GSC627 and GSC628 cells. G, H Immunofluorescence assays (G) and western blot (H) of GBM cells showing the localization of PRMT3. Scale bars, 25 μm.

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