Fig. 4: IL-18 deletion inhibited renal fibrosis induced by folic acid.
From: IL-18 deficiency ameliorates the progression from AKI to CKD
A The kidney size started shrinking from day 14 and became much smaller at day 30 after folic acid injection. B Renal mRNA expression of COL-1. C Renal protein expression of COL-1 analyzed by Western blotting and its semi-quantification. D Immunohistochemistry (IHC) staining and semi-quantification of COL-1 (red arrows) in renal cortex. Magnification, 400×, bar = 50 um. Data represent Mean ± SD (n = 6, #p < 0.05, other groups vs. day 0; *p < 0.05, KO vs. WT).
