Fig. 5: Mybpc3 deficiency promoted HIF-1α expression in fibroblasts. | Cell Death & Disease

Fig. 5: Mybpc3 deficiency promoted HIF-1α expression in fibroblasts.

From: MYBPC3 deficiency in cardiac fibroblasts drives their activation and contributes to fibrosis

Fig. 5

A, C Western blot analysis of HIF-1α and the related signaling molecules in WT and MYBPC3-KO fibroblasts treated with or without SB-431542 (10 µM). B, D Western blot analysis of HIF-1α and the related signaling molecules in WT and MYBPC3-KO fibroblasts treated with or without Oltipraz (10 µM). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001; ns, not significant.

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