Fig. 1: Correlation between linc00976 expression and clinical characteristics of CCA. | Cell Death & Disease

Fig. 1: Correlation between linc00976 expression and clinical characteristics of CCA.

From: JUND/linc00976 promotes cholangiocarcinoma progression and metastasis, inhibits ferroptosis by regulating the miR-3202/GPX4 axis

Fig. 1

a ISH analysis of linc00976 expression in CCA and adjacent non-tumor tissues. b The expression level of linc00976 was detected by RT-qPCR in 50 paired CCA tissues and adjacent non-cancerous tissues. c The fold changes of linc00976 expression in each paired sample are arranged from high to low. e Correlation between linc00976 expression and clinical stage. d Correlation between linc00976 expression and tumor size. f Correlation between linc00976 expression and distant metastasis. g CCA cases were divided into two groups according to the median value of linc00976 expression. Overall survival was analyzed by Kaplan–Meier survival analysis using the log-rank test. h ROC curve showing the diagnostic sensitivity and specificity of linc00976 in CCA. i. RT-qPCR analysis of relative expression levels of linc00976 in CCA cell lines and HIBECs. n.s. not significant, *P < 0.05, **P < 0.01, ***P < 0.001. CCA cholangiocarcinoma, HIBECs human intrahepatic biliary epithelial cells, ISH in situ hybridization, RT-qPCR reverse transcription-quantitative PCR.

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