Fig. 7: Exosomal miR-197-3p promotes angiogenesis and migration via silencing TIMP2/3 in HUVECs. | Cell Death & Disease

Fig. 7: Exosomal miR-197-3p promotes angiogenesis and migration via silencing TIMP2/3 in HUVECs.

From: Cancer-derived exosomal miR-197-3p confers angiogenesis via targeting TIMP2/3 in lung adenocarcinoma metastasis

Fig. 7

A The protein levels of TIMP3, VEGFR2, ERK and p-ERK in different HUVECs were determined by western blot. B The protein levels of TIMP2, MMP2 and MT1-MMP in different HUVECs were determined by western blot. C Angiogenesis was assessed by tube formation assay with quantitative analysis (right panel). D, E Cell migration was assessed by wound healing and transwell assays with quantitative analysis (right panel). Data were representative images or were expressed as the mean ± SD of n = 3 experiments. **P < 0.01, ***P < 0.001.

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