Table 2 Multivariate analysis by a Cox proportional hazards regression model.
Variable | PFS | OS | ||
|---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | |
Age (≤54 y vs. >54 y) | 1.006(0.974-1.039) | 0.404 | 0.994(0.568-1.739) | 0.982 |
Gender (male vs. female) | 0.739(0.363-1.504) | 0.708 | 0.683(0.327-1.425) | 0.309 |
Albumin (≤35 g/L vs. >35 g/L) | 0.684(0.314-1.493) | 0.341 | 0.499 (0.213-1.167) | 0.109 |
AFP ( ≤ 400ug/L vs. >400 ug/L) | 0.957(0.490-1.870) | 0.898 | 0.929 (0.469-1.841) | 0.833 |
Child-Pugh classification (A vs. B) | 1.146(0.634-2.074) | 0.652 | 1.178(0.646-2.149) | 0.593 |
Liver cirrhosis (absence vs. presence) | 1.375(0.721-2.623) | 0.333 | 1.170(0.624-2.196) | 0.624 |
Tumor differentiation (I / II vs. III/ IV) | 0.847(0.457-1.569) | 0.597 | 0.947(0.509-1.759) | 0.863 |
Tumor size (≤5 cm vs. >5 cm) | 1.362(0.795-2.333) | 0.260 | 1.352(0.771-2.371) | 0.293 |
Tumor number (single vs. multiple) | 1.137(0.463-2.794) | 0.779 | 1.132(0.450-2.847) | 0.793 |
TNM stage (I–II vs. III–IV) | 3.182(1.276-7.939) | 0.013* | 3.473(1.339-9.010) | 0.010* |
Venous invasion (absence vs. presence) | 2.306(1.145-4.647) | 0.019* | 2.500(1.253-4.987) | 0.009* |
TINCR expression (negative vs. positive) | 1.975(1.068-3.653) | 0.030* | 1.862(1.005-3.450) | 0.048* |
