Fig. 6: Mnk2 AS is essential for LINC00924 regulating lipid metabolic reprogramming. | Cell Death & Disease

Fig. 6: Mnk2 AS is essential for LINC00924 regulating lipid metabolic reprogramming.

From: LINC00924-induced fatty acid metabolic reprogramming facilitates gastric cancer peritoneal metastasis via hnRNPC-regulated alternative splicing of Mnk2

Fig. 6

A OCR analysis of MGC803-NC and LINC-OE cell lines treated with Mnk2b-block SSO or NC using palmitate as a metabolic substrate. B OCR analysis of AGS-NC and LINC-KD cell lines treated with Mnk2a-block SSO or NC using palmitate as a metabolic substrate. C Lipid droplet staining of AGS-NC and LINC-OE cells treated with Mnk2a-block SSO or NC. D Lipid droplet staining if MGC803-NC and LINC-KD cells treated with Mnk2a-block SSO or NC. E WB analysis of CPT1A, CD36, FABP4, p-P38, and PPARĪ± in MGC803-NC and LINC-OE cells treated with Mnk2b-block SSO or NC and AGS-NC and LINC00924-KD cells treated with Mnk2a-block SSO or NC.

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