Fig. 6: circFNDC3B promotes ASB6 degradation through RNF41-mediated ubiquitination. | Cell Death & Disease

Fig. 6: circFNDC3B promotes ASB6 degradation through RNF41-mediated ubiquitination.

From: m6A-modified circFNDC3B inhibits colorectal cancer stemness and metastasis via RNF41-dependent ASB6 degradation

Fig. 6

A The protein level of ASB6 was determined by western blotting with quantitative analysis. B The ubiquitination of ASB6 was assessed by co-IP in transfected CRC cells. C The interaction between ASB6 and RNF41 was detected by Co-IP. Normal IgG served as a negative control. D The protein levels of RNF41 and ASB6 were determined by western blotting with quantitative analysis in transfected CRC cells. E The protein level of ASB6 was determined by western blotting with quantitative analysis in transfected CRC cells. F The interaction between ASB6 and RNF41 in circFNDC3B-overexpressing cells was detected by Co-IP. *P < 0.05, **P < 0.01.

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